This value set includes codes based on the following rules:

<status value="draft"/><experimental value="false"/><publisher value="FHIR Project team"/><contact><telecom><system value="url"/><value value="http://hl7.org/fhir"/></telecom></contact><description value="Kinds of issues or contraindications, such as 'drug-drug interaction', 'duplicate therapy', etc."/><jurisdiction><coding><system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/><code value="001"/><display value="World"/></coding></jurisdiction><compose><include><system value="http://terminology.hl7.org/CodeSystem/v3-ActCode"/><filter><property value="concept"/><op value="is-a"/><value value="_AdministrationDetectedIssueCode"/></filter></include><include><system value="http://terminology.hl7.org/CodeSystem/v3-ActCode"/><filter><property value="concept"/><op value="is-a"/><value value="_ActSuppliedItemDetectedIssueCode"/></filter></include><include><system value="http://terminology.hl7.org/CodeSystem/v3-ActCode"/><filter><property value="concept"/><op value="is-a"/><value value="_ClinicalActionDetectedIssueCode"/></filter></include><include><system value="http://terminology.hl7.org/CodeSystem/v3-ActCode"/><filter><property value="concept"/><op value="is-a"/><value value="_SupplyDetectedIssueCode"/></filter></include></compose></ValueSet>