<?xml version="1.0" encoding="UTF-8"?>
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  Generated on Sun, Mar 26, 2023 15:21+1100 for FHIR v5.0.0 

  Note: the schemas &amp; schematrons do not contain all of the rules about what makes resources
  valid. Implementers will still need to be familiar with the content of the specification and with
  any profiles that apply to the resources in order to make a conformant implementation.

-->
<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns="http://hl7.org/fhir" xmlns:xhtml="http://www.w3.org/1999/xhtml" targetNamespace="http://hl7.org/fhir" elementFormDefault="qualified" version="1.0">
  <xs:include schemaLocation="fhir-base.xsd"/>
  <xs:element name="ResearchSubject" type="ResearchSubject">
    <xs:annotation>
      <xs:documentation xml:lang="en">A ResearchSubject is a participant or object which is the recipient of investigative activities in a research study.</xs:documentation>
    </xs:annotation>
  </xs:element>
  <xs:complexType name="ResearchSubject">
    <xs:annotation>
      <xs:documentation xml:lang="en">A ResearchSubject is a participant or object which is the recipient of investigative activities in a research study.</xs:documentation>
      <xs:documentation xml:lang="en">If the element is present, it must have either a @value, an @id, or extensions</xs:documentation>
    </xs:annotation>
    <xs:complexContent>
      <xs:extension base="DomainResource">
        <xs:sequence>
          <xs:element name="identifier" minOccurs="0" maxOccurs="unbounded" type="Identifier">
            <xs:annotation>
              <xs:documentation xml:lang="en">Identifiers assigned to this research subject for a study.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="status" minOccurs="1" maxOccurs="1" type="PublicationStatus">
            <xs:annotation>
              <xs:documentation xml:lang="en">The publication state of the resource (not of the subject).</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="progress" type="ResearchSubject.Progress" minOccurs="0" maxOccurs="unbounded">
            <xs:annotation>
              <xs:documentation xml:lang="en">The current state (status) of the subject and resons for status change where appropriate.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="period" minOccurs="0" maxOccurs="1" type="Period">
            <xs:annotation>
              <xs:documentation xml:lang="en">The dates the subject began and ended their participation in the study.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="study" minOccurs="1" maxOccurs="1" type="Reference">
            <xs:annotation>
              <xs:documentation xml:lang="en">Reference to the study the subject is participating in.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="subject" minOccurs="1" maxOccurs="1" type="Reference">
            <xs:annotation>
              <xs:documentation xml:lang="en">The record of the person, animal or other entity involved in the study.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="assignedComparisonGroup" minOccurs="0" maxOccurs="1" type="id">
            <xs:annotation>
              <xs:documentation xml:lang="en">The name of the arm in the study the subject is expected to follow as part of this study.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="actualComparisonGroup" minOccurs="0" maxOccurs="1" type="id">
            <xs:annotation>
              <xs:documentation xml:lang="en">The name of the arm in the study the subject actually followed as part of this study.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="consent" minOccurs="0" maxOccurs="unbounded" type="Reference">
            <xs:annotation>
              <xs:documentation xml:lang="en">A record of the patient's informed agreement to participate in the study.</xs:documentation>
           </xs:annotation>
          </xs:element>
        </xs:sequence>
      </xs:extension>
    </xs:complexContent>
  </xs:complexType>
  <xs:complexType name="ResearchSubject.Progress">
    <xs:annotation>
      <xs:documentation xml:lang="en">A ResearchSubject is a participant or object which is the recipient of investigative activities in a research study.</xs:documentation>
    </xs:annotation>
    <xs:complexContent>
      <xs:extension base="BackboneElement">
        <xs:sequence>
          <xs:element name="type" minOccurs="0" maxOccurs="1" type="CodeableConcept">
            <xs:annotation>
              <xs:documentation xml:lang="en">Identifies the aspect of the subject's journey that the state refers to.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="subjectState" minOccurs="0" maxOccurs="1" type="CodeableConcept">
            <xs:annotation>
              <xs:documentation xml:lang="en">The current state of the subject.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="milestone" minOccurs="0" maxOccurs="1" type="CodeableConcept">
            <xs:annotation>
              <xs:documentation xml:lang="en">The milestones the subject has passed through.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="reason" minOccurs="0" maxOccurs="1" type="CodeableConcept">
            <xs:annotation>
              <xs:documentation xml:lang="en">The reason for the state change.  If coded it should follow the formal subject state model.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="startDate" minOccurs="0" maxOccurs="1" type="dateTime">
            <xs:annotation>
              <xs:documentation xml:lang="en">The date when the new status started.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="endDate" minOccurs="0" maxOccurs="1" type="dateTime">
            <xs:annotation>
              <xs:documentation xml:lang="en">The date when the state ended.</xs:documentation>
           </xs:annotation>
          </xs:element>
        </xs:sequence>
      </xs:extension>
    </xs:complexContent>
  </xs:complexType>
</xs:schema>
