{"authoredOn":"2015-01-15","contained":[{"code":{"coding":[{"code":"1594660","display":"Alemtuzumab 10mg/ml (Lemtrada)","system":"http://www.nlm.nih.gov/research/umls/rxnorm"}]},"id":"med0303","resourceType":"Medication"}],"dosageInstruction":[{"additionalInstruction":[{"text":"Rapidly increase dose until tolerated"},{"text":"Administer on alternate days"}],"doseAndRate":[{"doseQuantity":{"code":"mg","system":"http://unitsofmeasure.org","unit":"mg","value":3},"type":{"coding":[{"code":"ordered","display":"Ordered","system":"http://terminology.hl7.org/CodeSystem/dose-rate-type"}]}}],"method":{"coding":[{"code":"422145002","display":"Inject - dosing instruction imperative (qualifier value)","system":"http://snomed.info/sct"}]},"route":{"coding":[{"code":"47625008","display":"Intravenous route (qualifier value)","system":"http://snomed.info/sct"}]},"sequence":1,"text":"Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk","timing":{"repeat":{"duration":12,"durationUnit":"wk","frequency":3,"period":1,"periodUnit":"wk"}}},{"additionalInstruction":[{"text":"Rapidly increase dose until tolerated"},{"text":"Administer on alternate days"}],"doseAndRate":[{"doseQuantity":{"code":"mg","system":"http://unitsofmeasure.org","unit":"mg","value":10},"type":{"coding":[{"code":"ordered","display":"Ordered","system":"http://terminology.hl7.org/CodeSystem/dose-rate-type"}]}}],"method":{"coding":[{"code":"422145002","display":"Inject - dosing instruction imperative (qualifier value)","system":"http://snomed.info/sct"}]},"route":{"coding":[{"code":"47625008","display":"Intravenous route (qualifier value)","system":"http://snomed.info/sct"}]},"sequence":2,"text":"Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk","timing":{"repeat":{"duration":12,"durationUnit":"wk","frequency":3,"period":1,"periodUnit":"wk"}}},{"additionalInstruction":[{"text":"Rapidly increase dose until tolerated"},{"text":"Administer on alternate days"}],"doseAndRate":[{"doseQuantity":{"code":"mg","system":"http://unitsofmeasure.org","unit":"mg","value":30},"type":{"coding":[{"code":"ordered","display":"Ordered","system":"http://terminology.hl7.org/CodeSystem/dose-rate-type"}]}}],"method":{"coding":[{"code":"422145002","display":"Inject - dosing instruction imperative (qualifier value)","system":"http://snomed.info/sct"}]},"route":{"coding":[{"code":"47625008","display":"Intravenous route (qualifier value)","system":"http://snomed.info/sct"}]},"sequence":3,"text":"Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk","timing":{"repeat":{"duration":12,"durationUnit":"wk","frequency":3,"period":1,"periodUnit":"wk"}}}],"id":"medrx0317","identifier":[{"system":"http://www.bmc.nl/portal/prescriptions","use":"official","value":"12345689"}],"intent":"order","medication":{"reference":{"reference":"#med0303"}},"reason":[{"concept":{"coding":[{"code":"92814006","display":"Chronic Lymphoid Leukemia (disorder)","system":"http://snomed.info/sct"}]}}],"requester":{"display":"Patrick Pump","reference":"Practitioner/f007"},"resourceType":"MedicationRequest","status":"completed","subject":{"display":"Donald Duck","reference":"Patient/pat1"},"text":{"div":"

Generated Narrative: MedicationRequest

Resource MedicationRequest "medrx0317"

identifier: id:\u00a012345689\u00a0(use:\u00a0OFFICIAL)

status: completed

intent: order

Medications

-Reference
*

code: Alemtuzumab 10mg/ml (Lemtrada) (RxNorm#1594660)

subject: Patient/pat1: Donald Duck "Donald DUCK"

authoredOn: 2015-01-15

requester: Practitioner/f007: Patrick Pump "Simone HEPS"

Reasons

-Concept
*Chronic Lymphoid Leukemia (disorder) (SNOMED CT#92814006)

dosageInstruction

sequence: 1

text: Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk

additionalInstruction: Rapidly increase dose until tolerated (), Administer on alternate days ()

timing: Duration 12weeks, 3 per 1 weeks

route: Intravenous route (qualifier value) (SNOMED CT#47625008)

method: Inject - dosing instruction imperative (qualifier value) (SNOMED CT#422145002)

doseAndRate

dosageInstruction

sequence: 2

text: Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk

additionalInstruction: Rapidly increase dose until tolerated (), Administer on alternate days ()

timing: Duration 12weeks, 3 per 1 weeks

route: Intravenous route (qualifier value) (SNOMED CT#47625008)

method: Inject - dosing instruction imperative (qualifier value) (SNOMED CT#422145002)

doseAndRate

dosageInstruction

sequence: 3

text: Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk

additionalInstruction: Rapidly increase dose until tolerated (), Administer on alternate days ()

timing: Duration 12weeks, 3 per 1 weeks

route: Intravenous route (qualifier value) (SNOMED CT#47625008)

method: Inject - dosing instruction imperative (qualifier value) (SNOMED CT#422145002)

doseAndRate

","status":"generated"}}