<?xml version="1.0" encoding="UTF-8"?>

<CodeSystem xmlns="http://hl7.org/fhir">
  <id value="genomicstudy-changetype"/>
  <meta>
    <lastUpdated value="2023-03-25T23:21:02.749-05:00"/>
    <profile value="http://hl7.org/fhir/StructureDefinition/shareablecodesystem"/>
  </meta>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml">
      <p>This code system 
        <code>http://hl7.org/fhir/genomicstudy-changetype</code> defines the following codes:
      </p>
      <table class="codes">
        <tr>
          <td style="white-space:nowrap">
            <b>Code</b>
          </td>
          <td>
            <b>Display</b>
          </td>
          <td>
            <b>Definition</b>
          </td>
        </tr>
        <tr>
          <td style="white-space:nowrap">DNA
            <a name="genomicstudy-changetype-DNA"> </a>
          </td>
          <td>DNA change</td>
          <td>Change that involves Deoxyribonucleic acid (DNA) sequences.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">RNA
            <a name="genomicstudy-changetype-RNA"> </a>
          </td>
          <td>RNA change</td>
          <td>Change that involves Ribonucleic Acid (RNA) sequences.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">AA
            <a name="genomicstudy-changetype-AA"> </a>
          </td>
          <td>Protein/amino Acids change </td>
          <td>Change that involves Amino Acid (AA) or protein sequences.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">CHR
            <a name="genomicstudy-changetype-CHR"> </a>
          </td>
          <td>Chromosomal changes</td>
          <td>Change that involves number or strcture of chromosomes.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">CNV
            <a name="genomicstudy-changetype-CNV"> </a>
          </td>
          <td>Copy number variations</td>
          <td>Change that involves copy number variations among various genomes.</td>
        </tr>
      </table>
    </div>
  </text>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-wg">
    <valueCode value="cg"/>
  </extension>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status">
    <valueCode value="trial-use"/>
  </extension>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm">
    <valueInteger value="1"/>
  </extension>
  <url value="http://hl7.org/fhir/genomicstudy-changetype"/>
  <identifier>
    <system value="urn:ietf:rfc:3986"/>
    <value value="urn:oid:2.16.840.1.113883.4.642.4.1977"/>
  </identifier>
  <version value="5.0.0"/>
  <name value="GenomicStudyChangeType"/>
  <title value="Genomic Study Change Type"/>
  <status value="active"/>
  <experimental value="true"/>
  <date value="2022-08-17T15:48:24-05:00"/>
  <publisher value="HL7 (FHIR Project)"/>
  <contact>
    <telecom>
      <system value="url"/>
      <value value="http://hl7.org/fhir"/>
    </telecom>
    <telecom>
      <system value="email"/>
      <value value="fhir@lists.hl7.org"/>
    </telecom>
  </contact>
  <description value="The change type relevant to GenomicStudy analysis."/>
  <jurisdiction>
    <coding>
      <system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/>
      <code value="001"/>
      <display value="World"/>
    </coding>
  </jurisdiction>
  <caseSensitive value="true"/>
  <valueSet value="http://hl7.org/fhir/ValueSet/genomicstudy-changetype"/>
  <content value="complete"/>
  <concept>
    <code value="DNA"/>
    <display value="DNA change"/>
    <definition value="Change that involves Deoxyribonucleic acid (DNA) sequences."/>
  </concept>
  <concept>
    <code value="RNA"/>
    <display value="RNA change"/>
    <definition value="Change that involves Ribonucleic Acid (RNA) sequences."/>
  </concept>
  <concept>
    <code value="AA"/>
    <display value="Protein/amino Acids change "/>
    <definition value="Change that involves Amino Acid (AA) or protein sequences."/>
  </concept>
  <concept>
    <code value="CHR"/>
    <display value="Chromosomal changes"/>
    <definition value="Change that involves number or strcture of chromosomes."/>
  </concept>
  <concept>
    <code value="CNV"/>
    <display value="Copy number variations"/>
    <definition value="Change that involves copy number variations among various genomes."/>
  </concept>
</CodeSystem>